Knowledge · Dr. med. Anna Margareta Wagner · FMH

Testosterone in Women – Off-Label Use in Basel (Dr. Wagner)

Dr. med. Anna Margareta Wagner
Medically reviewed by Dr. med. Anna Margareta WagnerBoard-certified FMH gynecologist · Basel

Testosterone in women: indication, limitations, off-label use, doping, voice changes – menopause medicine Basel.

Medically reviewed on · Dr. med. Anna Margareta Wagner, FMH Gynäkologie und GeburtshilfeSpalenvorstadt 3 · 4051 Basel · +41 61 666 62 10
  • FMH Gynecology

    Board certified

  • SGGG

    Member

  • Colposcopy diploma

    Certified

  • DE · EN

    Languages

  • Spalenvorstadt 3

    4051 Basel

At a glance

Testosterone is a hormone produced naturally in the body, also by women in small amounts. In menopause medicine, it can be used in selected situations as an adjunct to hormone therapy – not as an anti-ageing treatment, not for general performance enhancement.

Many claims circulate about testosterone and energy, muscle mass, mood and «optimisation». The medical evidence supports only a narrow indication: persistently reduced sexual desire after menopause with personal distress, after excluding other causes.

Postmenopausal women with a sexual desire disorder that is personally experienced as distressing – and in whom physical, psychological, relationship-related and medication-related causes have been carefully assessed.

Key facts
  • Not a routine part of every hormone therapy.
  • Treatment only with a clear indication – not because of a low lab value.
  • Not used for anti-ageing, muscle building, energy or concentration.
  • In Switzerland: off-label use – as a self-pay service.
  • Not started in voice-dependent professions (possible permanent voice changes).
  • For competitive athletes: WADA ban applies, a TUE may be required.
Causes

After menopause, concentrations of ovarian sex hormones decline – including androgens. Whether a lower testosterone level causes symptoms cannot be determined from the lab result alone: sexual desire arises from an interplay of physical, psychological, relationship-related and life-context factors.

Risk factors

  • Pain during intercourse, vaginal dryness
  • Medications (e.g. certain antidepressants, anti-hormone therapy)
  • Physical illness and sleep disorders
  • Psychological strain, depression, anxiety
  • Relationship and psychosocial factors

Frequency

Persistently distressing reduced desire after menopause affects a relevant minority of women – reliable figures vary depending on definition and study.

Symptoms & findings

Typical symptoms

  • Persistently reduced sexual desire – personally distressing
  • Reduced sexual responsiveness despite treated vaginal symptoms

Common incidental findings

  • General tiredness, lack of drive, concentration problems without further hormonal indicators
  • Weight gain, muscle loss, «signs of ageing» without clear hormonal cause

When is it detected?

Bring up the topic actively if reduced desire is burdening you or your relationship. Honest assessment is the basis for a sound treatment decision.

Diagnostics

The basis is a thorough medical history. Other causes – vaginal dryness, pain, medications, psychological strain, relationship factors – are specifically assessed and, where possible, treated first. A testosterone level does not diagnose a sexual desire disorder. Blood tests are nevertheless used during treatment to detect an already elevated baseline level and to avoid overdosing.

Examinations

  • Sexual history and psychosocial assessment
  • Gynaecological assessment – vulvovaginal condition, pain, dryness
  • Review of medications and comorbidities
  • Baseline testosterone level before starting and follow-up under therapy

What do the findings mean?

The goal is not the highest or an «optimal» testosterone level, but clinical improvement without exceeding the physiological female range.

Treatment

Watchful waiting

If other causes (e.g. vaginal dryness, medications, depression, relationship factors) predominate, these are treated first. Testosterone therapy is then often no longer needed. How we treat dryness and pain in the intimate area is explained under Intimate health.

Medication

If, after careful assessment, testosterone treatment is considered, it is used off-label in Switzerland: the available preparations are approved for male hypogonadism, and use in women falls outside the approved indication and dosage. Prerequisites are a clear medical justification, thorough counselling, a low starting dose and regular follow-up. Counselling, medication and follow-up are self-pay services – billing through health insurance is not offered for this treatment.

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Frequently asked questions

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About the author

Medically responsible.

Dr. med. Anna Margareta Wagner is a board-certified FMH specialist in gynecology and obstetrics with her own practice at Spalenvorstadt 3 in Basel. Special focus on surgical gynecology; further focus areas: gynecological check-ups, colposcopy and dysplasia consultations, intimate surgery, pregnancy care, and consultations for girls and adolescents.

  • FMH specialist certification in gynecology and obstetrics
  • Special focus: surgical gynecology
  • SGGG member
  • Certified colposcopy diploma
  • Languages: German, English
  • Service area: Basel-Stadt, Basel-Landschaft, northwestern Switzerland

The content on this page is reviewed regularly against current specialist medical recommendations.

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